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Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects ONDANSETRON is the generic name for Zofran. Common Zofran side effects may include: diarrhea or constipation; headache; drowsiness; or. Since 2007, there have been nearly 50 approved ANDAs to sell generic Zofran (ondansetron). Initial and repeat courses of moderately emetogenic cancer chemotherapy. If there is a threat for queasiness or. Zofran enjoyed this privilege in the United States between January 4, 1991 and mid-2007. Updated 19 minutes 45 seconds ago|8/27/2022 7:27:52 PM. Then administer 8 mg twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy. Problems with your skin or hair. 0 Answers/Comments A brand-name drug maker such as GlaxoSmithKline (GSK) which makes Zofran has the exclusive right to sell and market that drug so long as it enjoys patent protection. It’s also available as a generic drug. 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